Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM50246598
Substrate
n/a
Meas. Tech.
ChEMBL_489239 (CHEMBL989986)
EC50
5470±n/a nM
Citation
 Lewin, AH; Navarro, HA; Mascarella, SW Structure-activity correlations for beta-phenethylamines at human trace amine receptor 1. Bioorg Med Chem 16:7415-23 (2008) [PubMed]  Article 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TA1 | TAAR1 | TAAR1_HUMAN | TAR1 | TRAR1 | trace amine-associated receptor 1
Type:
PROTEIN
Mol. Mass.:
39107.47
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792734
Residue:
339
Sequence:
MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
  
Inhibitor
Name:
BDBM50246598
Synonyms:
2-methyl-1-phenylpropan-2-amine | CHEMBL1574 | PHENTERMINE | alpha,alpha-Dimethylphenethylamine
Type:
Small organic molecule
Emp. Form.:
C10H15N
Mol. Mass.:
149.2328
SMILES:
CC(C)(N)Cc1ccccc1
Structure:
Search PDB for entries with ligand similarity: