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Target
Trace amine-associated receptor 1
Ligand
BDBM50005267
Substrate
n/a
Meas. Tech.
ChEMBL_489239 (CHEMBL989986)
EC50
7190±n/a nM
Citation
 Lewin, AH; Navarro, HA; Mascarella, SW Structure-activity correlations for beta-phenethylamines at human trace amine receptor 1. Bioorg Med Chem 16:7415-23 (2008) [PubMed]  Article 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TA1 | TAAR1 | TAAR1_HUMAN | TAR1 | TRAR1 | trace amine-associated receptor 1
Type:
PROTEIN
Mol. Mass.:
39107.47
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792734
Residue:
339
Sequence:
MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
  
Inhibitor
Name:
BDBM50005267
Synonyms:
2,5-dimethoxy-4-bromophenethylamine | 2-(4-Bromo-2,5-dimethoxy-phenyl)-ethylamine | 2-(4-bromo-2,5-dimethoxyphenyl)ethylamine | CHEMBL292821
Type:
Small organic molecule
Emp. Form.:
C10H14BrNO2
Mol. Mass.:
260.128
SMILES:
COc1cc(CCN)c(OC)cc1Br
Structure:
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