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Target
Transcriptional activator protein TraR
Ligand
BDBM50265809
Substrate
n/a
Meas. Tech.
ChEMBL_543882 (CHEMBL1016857)
IC50
3300±n/a nM
Citation
 Geske, GD; Mattmann, ME; Blackwell, HE Evaluation of a focused library of N-aryl L-homoserine lactones reveals a new set of potent quorum sensing modulators. Bioorg Med Chem Lett 18:5978-81 (2008) [PubMed]  Article 
Target
Name:
Transcriptional activator protein TraR
Synonyms:
TRAR_RHIRD | traR
Type:
PROTEIN
Mol. Mass.:
26741.83
Organism:
Rhizobium radiobacter
Description:
ChEMBL_765233
Residue:
234
Sequence:
MQHWLDKLTDLAAIEGDECILKTGLADIADHFGFTGYAYLHIQHRHITAVTNYHRQWQSTYFDKKFEALDPVVKRARSRKHIFTWSGEHERPTLSKDERAFYDHASDFGIRSGITIPIKTANGFMSMFTMASDKPVIDLDREIDAVAAAATIGQIHARISFLRTTPTAEDAAWLDPKEATYLRWIAVGKTMEEIADVEGVKYNSVRVKLREAMKRFDVRSKAHLTALAIRRKLI
  
Inhibitor
Name:
BDBM50265809
Synonyms:
(S)-3-(4-chlorophenyl)-N-(2-oxotetrahydrofuran-3-yl)propanamide | CHEMBL457113
Type:
Small organic molecule
Emp. Form.:
C13H14ClNO3
Mol. Mass.:
267.708
SMILES:
Clc1ccc(CCC(=O)N[C@H]2CCOC2=O)cc1 |r|
Structure:
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