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Target
Amine oxidase [flavin-containing] B
Ligand
BDBM50246152
Substrate
n/a
Meas. Tech.
ChEMBL_558908 (CHEMBL1022587)
IC50
170220±n/a nM
Citation
 Jayaprakash, V; Sinha, BN; Ucar, G; Ercan, A Pyrazoline-based mycobactin analogues as MAO-inhibitors. Bioorg Med Chem Lett 18:6362-8 (2008) [PubMed]  Article 
Target
Name:
Amine oxidase [flavin-containing] B
Synonyms:
Monoamine oxidase B (rMAO-B) | Monoamine oxidase | Monoamine oxidase B (MAO-B) | Monoamine oxidase-B (MAO-B) | Amine oxidase [flavin-containing] B | Amine oxidase (flavin-containing) B | Monoamine oxidase type B (MAOB) | AOFB_RAT | Maob | Monoamine Oxidase Type B (MAO-B)
Type:
Enzyme
Mol. Mass.:
58469.65
Organism:
Rat
Description:
P19643
Residue:
520
Sequence:
MSNKCDVIVVGGGISGMAAAKLLHDCGLSVVVLEARDRVGGRTYTIRNKNVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHFVKGKSYAFRGPFPPVWNPITYLDYNNLWRTMDEMGQEIPSDAPWKAPLAEEWDYMTMKELLDKICWTNSTKQIATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFIGGSGQVSERIKDILGDRVKLERPVIHIDQTGENVVVKTLNHEIYEAKYVISAIPPVLGMKIHHSPPLPILRNQLITRVPLGSVIKCMVYYKEPFWRKKDFCGTMVIEGEEAPIAYTLDDTKPDGSCAAIMGFILAHKARKLVRLTKEERLRKLCELYAKVLNSQEALQPVHYEEKNWCEEQYSGGCYTAYFPPGILTQYGRVLRQPVGKIFFAGTETASHWSGYMEGAVEAGERAAREILHAIGKIPEDEIWQPEPESVDVPARPITNTFLERHLPSVPGLLKLLGLTTILSATALGFLAHKKGLFVRF
  
Inhibitor
Name:
BDBM50246152
Synonyms:
3-(2,4-dihydroxyphenyl)-5-(4-hydroxy-3-methoxyphenyl)-N-(2-methoxyphenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide | CHEMBL471356
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: