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Target
Amine oxidase [flavin-containing] A
Ligand
BDBM15581
Substrate
n/a
Meas. Tech.
ChEMBL_558907 (CHEMBL1022586)
IC50
2050±n/a nM
Citation
 Jayaprakash, V; Sinha, BN; Ucar, G; Ercan, A Pyrazoline-based mycobactin analogues as MAO-inhibitors. Bioorg Med Chem Lett 18:6362-8 (2008) [PubMed]  Article 
Target
Name:
Amine oxidase [flavin-containing] A
Synonyms:
Monoamine oxidase A (MAO-A) | Monoamine Oxidase Type A (MAO-A) | Monoamine oxidase type A (MAOA) | Amine oxidase [flavin-containing] A | Amine oxidase (flavin-containing) A | Monoamine oxidase A (rMAO-A) | AOFA_RAT | Maoa | Monoamine oxidase
Type:
Enzyme
Mol. Mass.:
59515.21
Organism:
Rat
Description:
n/a
Residue:
526
Sequence:
MTDLEKPNLAGHMFDVGLIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVKWVDVGGAYVGPTQNRILRLSKELGIETYKVNVNERLVQYVKGKTYPFRGAFPPVWNPLAYLDYNNLWRTMDEMGKEIPVDAPWQARHAQEWDKMTMKDLIDKICWTKTAREFAYLFVNINVTSEPHEVSALWFLWYVRQCGGTARIFSVTNGGQERKFVGGSGQVSEQIMGLLGDKVKLSSPVTYIDQTDDNIIVETLNHEHYECKYVISAIPPILTAKIHFKPELPPERNQLIQRLPMGAVIKCMVYYKEAFWKKKDYCGCMIIEDEEAPIAITLDDTKPDGSLPAIMGFILARKADRQAKLHKDIRKRKICELYAKVLGSQEALYPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYGRVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREVLNALGKVAKKDIWVEEPESKDVPAIEITHTFLERNLPSVPGLLKITGVSTSVALLCFVLYKIKKLPC
  
Inhibitor
Name:
BDBM15581
Synonyms:
US8633208, Clorgyline | [3-(2,4-dichlorophenoxy)propyl](methyl)prop-2-yn-1-ylamine | CHEMBL8706 | CLG | CLORGILINE | N-[3-(2,4-dichlorophenoxy)propyl]-N-methyl-prop-2-yn-1-amine | Clorgyline | US9603833, Clorgyline
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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