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Target
Neuronal acetylcholine receptor subunit alpha-7
Ligand
BDBM50254542
Substrate
n/a
Meas. Tech.
ChEMBL_558776 (CHEMBL1020769)
Ki
>1000000±n/a nM
Citation
 Hansen, CP; Jensen, AA; Balle, T; Bitsch-Jensen, K; Hassan, MM; Liljefors, T; Frølund, B Carbamoylcholine analogs as nicotinic acetylcholine receptor agonists--structural modifications of 3-(dimethylamino)butyl dimethylcarbamate (DMABC). Bioorg Med Chem Lett 19:87-91 (2008) [PubMed]  Article 
Target
Name:
Neuronal acetylcholine receptor subunit alpha-7
Synonyms:
Cholinergic, Nicotinic Alpha7 | NACHRA7 | CHRNA7 | Neuronal acetylcholine receptor protein alpha-7 subunit | Nicotinic acetylcholine receptor alpha-7 (alpha7 nAChR) | ACHA7_HUMAN | Neuronal acetylcholine receptor subunit alpha-7 (nAChR-alpha 7)
Type:
n/a
Mol. Mass.:
56448.33
Organism:
Human
Description:
CHRNA7 (NACHRA7)
Residue:
502
Sequence:
MRCSPGGVWLALAASLLHVSLQGEFQRKLYKELVKNYNPLERPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGIPGKRSERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWTRVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNLLYIGFRGLDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIANRFRCQDESEAVCSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA
  
Inhibitor
Name:
BDBM50254542
Synonyms:
O-3-(dimethylamino)butyl dimethylcarbamothioate | CHEMBL468903
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: