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Target
Amine oxidase [flavin-containing] B
Ligand
BDBM15579
Substrate
n/a
Meas. Tech.
ChEMBL_495008 (CHEMBL997738)
IC50
2010.0±n/a nM
Citation
 Gökhan-Kelekçi, N; Koyunoqlu, S; Yabanoqlu, S; Yesilada, K; Ozgen, O; Uçar, G; Erol, K; Kendi, E; Yesilada, A New pyrazoline bearing 4(3H)-quinazolinone inhibitors of monoamine oxidase: synthesis, biological evaluation, and structural determinants of MAO-A and MAO-B selectivity. Bioorg Med Chem 17:675-89 (2009) [PubMed]  Article 
Target
Name:
Amine oxidase [flavin-containing] B
Synonyms:
Monoamine oxidase B (rMAO-B) | Monoamine oxidase | Monoamine oxidase B (MAO-B) | Monoamine oxidase-B (MAO-B) | Amine oxidase [flavin-containing] B | Amine oxidase (flavin-containing) B | Monoamine oxidase type B (MAOB) | AOFB_RAT | Maob | Monoamine Oxidase Type B (MAO-B)
Type:
Enzyme
Mol. Mass.:
58469.65
Organism:
Rat
Description:
P19643
Residue:
520
Sequence:
MSNKCDVIVVGGGISGMAAAKLLHDCGLSVVVLEARDRVGGRTYTIRNKNVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHFVKGKSYAFRGPFPPVWNPITYLDYNNLWRTMDEMGQEIPSDAPWKAPLAEEWDYMTMKELLDKICWTNSTKQIATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFIGGSGQVSERIKDILGDRVKLERPVIHIDQTGENVVVKTLNHEIYEAKYVISAIPPVLGMKIHHSPPLPILRNQLITRVPLGSVIKCMVYYKEPFWRKKDFCGTMVIEGEEAPIAYTLDDTKPDGSCAAIMGFILAHKARKLVRLTKEERLRKLCELYAKVLNSQEALQPVHYEEKNWCEEQYSGGCYTAYFPPGILTQYGRVLRQPVGKIFFAGTETASHWSGYMEGAVEAGERAAREILHAIGKIPEDEIWQPEPESVDVPARPITNTFLERHLPSVPGLLKLLGLTTILSATALGFLAHKKGLFVRF
  
Inhibitor
Name:
BDBM15579
Synonyms:
US8633208, Deprenyl | CHEMBL972 | L-Deprenyl | SLG | DEPRENYL | methyl[(2R)-1-phenylpropan-2-yl]prop-2-yn-1-ylamine | N-methyl-N-[(2R)-1-phenylpropan-2-yl]prop-2-yn-1-amine | Selegiline | US9469653, Selegiline
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: