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Target
Cholecystokinin receptor type A
Ligand
BDBM50286147
Substrate
n/a
Meas. Tech.
ChEBML_49403
IC50
4500±n/a nM
Citation
 Holladay, MW; Bennett, MJ; Bai, H; Ralston, JW; Kerwin, JF; Stashko, M; Miller, TR; O'Neill, AB; Nadzan, AM; Brioni, J; Lin, CW Amino acid-derived piperidides as novel CCKB ligands with anxiolytic-like properties Bioorg Med Chem Lett 5:3057-3062 (1995)    Article 
Target
Name:
Cholecystokinin receptor type A
Synonyms:
CCK-A receptor | CCK-AR | CCK1-R | CCKAR | CCKAR_CAVPO | Cholecystokinin A receptor | Cholecystokinin receptor type A | Cholecystokinin-1 receptor
Type:
n/a
Mol. Mass.:
48229.77
Organism:
Cavia porcellus
Description:
n/a
Residue:
430
Sequence:
MDVVDSLFVNGSNITSACELGFENETLFCLDRPRPSKEWQPAVQILLYSLIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPSLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTGNMCRFLLPNDVMQQTWHTFLLLILFLIPGIVMMVAYGLISLELYQGIKFDAIQKKSAKERKTSTGSSGPMEDSDGCYLQKSRHPRKLELRQLSPSSSGSNRINRIRSSSSTANLMAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAERHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGTPGVRGEMGEEEEGRTTGASLSRYSYSHMSTSAPPP
  
Inhibitor
Name:
BDBM50286147
Synonyms:
CHEMBL319196 | [(S)-2-(4-Benzoyl-piperidin-1-yl)-1-(1H-indol-3-ylmethyl)-2-oxo-ethyl]-carbamic acid tert-butyl ester
Type:
Small organic molecule
Emp. Form.:
C28H33N3O4
Mol. Mass.:
475.5793
SMILES:
CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N1CCC(CC1)C(=O)c1ccccc1
Structure:
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