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Target
Neuropeptide Y receptor type 1
Ligand
BDBM50287536
Substrate
n/a
Meas. Tech.
ChEBML_144144
Ki
58±n/a nM
Citation
 Wright, J; Bolton, G; Creswell, M; Downing, D; Georgic, L; Heffner, T; Hodges, J; MacKenzie, R; Wise, L 8-amino-6-(arylsulphonyl)-5-nitroquinolines: novel nonpeptide neuropeptide Y1 receptor antagonists Bioorg Med Chem Lett 6:1809-1814 (1996)    Article  BDB Entry
Target
Name:
Neuropeptide Y receptor type 1
Synonyms:
NPY-Y1 | NPY1-R | neuropeptide Y receptor Y1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44399.07
Organism:
Homo sapiens (Human)
Description:
NPY-Y1 NPY1R HUMAN::P25929
Residue:
384
Sequence:
MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEKI
  
Inhibitor
Name:
BDBM50287536
Synonyms:
6-(2-Fluoro-benzenesulfonyl)-5-nitro-quinolin-8-ylamine | CHEMBL52643
Type:
Small organic molecule
Emp. Form.:
C15H10FN3O4S
Mol. Mass.:
347.321
SMILES:
Nc1cc(c([N+]([O-])=O)c2cccnc12)S(=O)(=O)c1ccccc1F
Structure:
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