Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50285554
Substrate
n/a
Meas. Tech.
ChEBML_28844
Ki
428±n/a nM
Citation
 Poulsen, SA; Quin, RJ Pyrazolo[3,4-d]pyrimidines: C4, C6 substitution leads to adenosine A1 receptor selectivity Bioorg Med Chem Lett 6:357-360 (1996)    Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50285554
Synonyms:
3-(4-Amino-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylsulfanyl)-propionamide | CHEMBL79201
Type:
Small organic molecule
Emp. Form.:
C14H14N6OS
Mol. Mass.:
314.366
SMILES:
NC(=O)CCSc1nc(N)c2cnn(-c3ccccc3)c2n1
Structure:
Search PDB for entries with ligand similarity: