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Target
Carbonic anhydrase 2
Ligand
BDBM50288888
Substrate
n/a
Meas. Tech.
ChEBML_45054
Kd
170±n/a nM
Citation
 Sigal, GB; Whitesides, GM Benzenesulfonamide-peptide conjugates as probes for secondary binding sites near the active site of carbonic anhydrase Bioorg Med Chem Lett 6:559-564 (1996)    Article 
Target
Name:
Carbonic anhydrase 2
Synonyms:
CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II)
Type:
Enzyme
Mol. Mass.:
29250.71
Organism:
Homo sapiens (Human)
Description:
P00918
Residue:
260
Sequence:
MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
  
Inhibitor
Name:
BDBM50288888
Synonyms:
3-(4-Methoxy-phenyl)-2-{2-[2-(4-sulfamoyl-benzoylamino)-acetylamino]-acetylamino}-propionic acid | CHEMBL2371113
Type:
Small organic molecule
Emp. Form.:
C21H24N4O8S
Mol. Mass.:
492.502
SMILES:
COc1ccc(C[C@H](NC(=O)CNC(=O)CNC(=O)c2ccc(cc2)S(N)(=O)=O)C(O)=O)cc1 |r|
Structure:
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