Reaction Details
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Report a problem with these dataTarget
Vasopressin V2 receptor
Ligand
BDBM35667
Substrate
n/a
Meas. Tech.
ChEBML_211240
IC50
3.3±n/a nM
Citation
Moutiez, M; Lippens, G; Sergheraert, C; Tartar, A Vasopressin trisulphide: synthesis, NMR study and affinity studies with V1 and V2 subtypes receptors Bioorg Med Chem Lett 7:719-724 (1997) Article More Info.:
Target
Name:
Vasopressin V2 receptor
Synonyms:
V2R_PIG | AVPR2
Type:
PROTEIN
Mol. Mass.:
40556.17
Organism:
Pig
Description:
ChEMBL_214870
Residue:
370
Sequence:
MLRATTSAVPRALSWPAAPGNGSEREPLDDRDPLLARVELALLSTVFVAVALSNGLVLGALVRRGRRGRWAPMHVFIGHLCLADLAVALFQVLPQLAWDATYRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGGGARWNRPVLVAWAFSLLLSLPQLFIFAQRDVGDGSGVLDCWASFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHTSLVPGPAERAGGHRGGRRAGSPREGARVSAAMAKTARMTLVIVAVYVLCWAPFFLVQLWSVWDPKAPREGPPFVLLMLLASLNSCTNPWIYASFSSSISSELRSLLCCPRRRTPPSLRPQEESCATASSFSARDTSS
Inhibitor
Name:
BDBM35667
Synonyms:
[3H]Argipressin tannate | AVP | [3H]Arginine vasopressin | CHEMBL373742 | [3H]vasopressin | US10131692, 44 (AVP)
Type:
radiolabeled ligand
Emp. Form.:
C46H17N15O12S2
Mol. Mass.:
1035.06
SMILES:
[#7]-[#6@H]-1-[#6]-[#16]-[#16]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-c2ccccc2)-[#7]-[#6](=O)-[#6@H](-[#6]-c2ccc(-[#8])cc2)-[#7]-[#6]-1=O)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6](-[#7])=O
Structure:
