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Target
Cysteinyl leukotriene receptor 1
Ligand
BDBM50292408
Substrate
n/a
Meas. Tech.
ChEMBL_486186 (CHEMBL1016594)
Ki
0.600000±n/a nM
Citation
 Sweetnam, PM; Caldwell, L; Lancaster, J; Jr., CB; McMillan, B; Kinnier, WJ; Price, CH The Role of Receptor Binding in Drug Discovery J Nat Prod 56:441-455 (1993) [PubMed]  Article 
Target
Name:
Cysteinyl leukotriene receptor 1
Synonyms:
Leukotriene Cysteinyl 1 | Cysteinyl leukotriene receptor | HMTMF81 | LTD4 receptor | Cysteinyl leukotriene D4 receptor | HG55 | CLTR1_HUMAN | CYSLTR1 | CYSLT1 | Cysteinyl leukotriene receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38565.16
Organism:
Human
Description:
Leukotriene Cysteinyl 1 CYSLTR1 HUMAN::Q9Y271
Residue:
337
Sequence:
MDETGNLTVSSATCHDTIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLIKTYHKKSAFQVYMINLAVADLLCVCTLPLRVVYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSFFRCIAIVFPVQNINLVTQKKARFVCVGIWIFVILTSSPFLMAKPQKDEKNNTKCFEPPQDNQTKNHVLVLHYVSLFVGFIIPFVIIIVCYTMIILTLLKKSMKKNLSSHKKAIGMIMVVTAAFLVSFMPYHIQRTIHLHFLHNETKPCDSVLRMQKSVVITLSLAASNCCFDPLLYFFSGGNFRKRLSTFRKHSLSSVTYVPRKKASLPEKGEEICKV
  
Inhibitor
Name:
BDBM50292408
Synonyms:
5S-hydroxy-6R-(S-cysteinylglycinyl)-7E,9E,11E,14Z-eicosatetraenoic acid | LTD4 | (R-(R*,S*-(E,E,Z,Z)))-N-(S-(1-(4-Carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-L-cysteinyl)glycine | CHEMBL288943 | leukotriene D4 | S-{(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]pentadeca-2,4,6,9-tetraen-1-yl}-L-cysteinylglycine
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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