Reaction Details Report a problem with these data
Target
Ribonuclease pancreatic
Ligand
BDBM50292714
Substrate
n/a
Meas. Tech.
ChEMBL_493877 (CHEMBL944248)
Ki
103000±n/a nM
Citation
 Samanta, A; Leonidas, DD; Dasgupta, S; Pathak, T; Zographos, SE; Oikonomakos, NG Morpholino, piperidino, and pyrrolidino derivatives of pyrimidine nucleosides as inhibitors of ribonuclease A: synthesis, biochemical, and crystallographic evaluation. J Med Chem 52:932-42 (2009) [PubMed]  Article 
Target
Name:
Ribonuclease pancreatic
Synonyms:
CAM-RNase A | RNAS1_BOVIN | RNASE1 | RNAse A | RNS1
Type:
Enzyme
Mol. Mass.:
16468.79
Organism:
Bison bison (American bison)
Description:
carboxamidomethylated RNase A
Residue:
150
Sequence:
MALKSLVLLSLLVLVLLLVRVQPSLGKETAAAKFERQHMDSSTSAASSSNYCNQMMKSRNLTKDRCKPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPNCAYKTTQANKHIIVACEGNPYVPVHFDASV
  
Inhibitor
Name:
BDBM50292714
Synonyms:
3'-N-piperidine-4-carboxyl-3'-deoxyara-uridine | CHEMBL461790
Type:
Small organic molecule
Emp. Form.:
C15H21N3O7
Mol. Mass.:
355.3431
SMILES:
OC[C@]1(O[C@H]([C@@H](O)[C@@H]1N1CCCCC1)n1ccc(=O)[nH]c1=O)C(O)=O |r|
Structure:
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