Reaction Details Report a problem with these data
Target
Ribonuclease pancreatic
Ligand
BDBM50292724
Substrate
n/a
Meas. Tech.
ChEMBL_493877 (CHEMBL944248)
Ki
6000±n/a nM
Citation
 Samanta, A; Leonidas, DD; Dasgupta, S; Pathak, T; Zographos, SE; Oikonomakos, NG Morpholino, piperidino, and pyrrolidino derivatives of pyrimidine nucleosides as inhibitors of ribonuclease A: synthesis, biochemical, and crystallographic evaluation. J Med Chem 52:932-42 (2009) [PubMed]  Article 
Target
Name:
Ribonuclease pancreatic
Synonyms:
CAM-RNase A | RNAS1_BOVIN | RNASE1 | RNAse A | RNS1
Type:
Enzyme
Mol. Mass.:
16468.79
Organism:
Bison bison (American bison)
Description:
carboxamidomethylated RNase A
Residue:
150
Sequence:
MALKSLVLLSLLVLVLLLVRVQPSLGKETAAAKFERQHMDSSTSAASSSNYCNQMMKSRNLTKDRCKPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPNCAYKTTQANKHIIVACEGNPYVPVHFDASV
  
Inhibitor
Name:
BDBM50292724
Synonyms:
CHEMBL460901 | URACIL ARABINOSE-3'-PHOSPHATE | arabinouridine 3'-phosphate
Type:
Small organic molecule
Emp. Form.:
C9H13N2O9P
Mol. Mass.:
324.1813
SMILES:
OC[C@H]1O[C@H]([C@@H](O)[C@@H]1OP(O)(O)=O)n1ccc(=O)[nH]c1=O |r|
Structure:
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