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Target
Isoform Cytoplasmic of Fumarate hydratase, mitochondrial (Cytoplasmic)
Ligand
BDBM50297823
Substrate
n/a
Meas. Tech.
ChEMBL_584091 (CHEMBL1058332)
Ki
80±n/a nM
Citation
 Ismail, FM; Levitsky, DO; Dembitsky, VM Aziridine alkaloids as potential therapeutic agents. Eur J Med Chem 44:3373-87 (2009) [PubMed]  Article 
Target
Name:
Isoform Cytoplasmic of Fumarate hydratase, mitochondrial (Cytoplasmic)
Synonyms:
FUMH_PIG | FH | Fumarate hydratase, mitochondrial (Cytoplasmic) | Fumarate hydratase, mitochondrial
Type:
PROTEIN
Mol. Mass.:
50108.62
Organism:
Pig
Description:
ChEMBL_584091
Residue:
467
Sequence:
MASQNSFRIEYDTFGELKVPNDKYYGAQTVRSTMNFKIGGVTERMPIPVIKAFGILKRAAAEVNQDYGLDPKIANAIMKAADEVAEGKLNDHFPLVVWQTGSGTQTNMNVNEVISNRAIEMLGGELGSKKPVHPNDHVNKSQSSNDTFPTAMHIAAAVEVHEALLPGLQKLHDALDAKSREFAQIIKIGRTHTQDAVPLTLGQEFSGYVQQVKYAITRIKAAMPRIYELAAGGTAVGTGLNTRIGFAEKVAAKVAALTGLPFVTAPNKFEALAAHDALVELSGAMNTTACSLMKIANDIRFLGSGPRSGLGELILPENEPGSSIMPGKVNPTQCEALTMVAAQVMGNHVAVTVGGSNGHFELNVFKPMMIKNVLHSARLLGDAAVSFTENCVVGIQANTERINKLMNESLMLVTALNPHIGYDKAAKIAKTAHKNGSTLKATAVELGYLTAEQFDEWVKPKDMLGPK
  
Inhibitor
Name:
BDBM50297823
Synonyms:
(2S,3S)-Aziridine-2,3-dicarboxylic acid | CHEMBL538419
Type:
Small organic molecule
Emp. Form.:
C4 H5 N O4
Mol. Mass.:
131.08679
SMILES:
OC(=O)[C@H]1N[C@@H]1C(O)=O |r|
Structure:
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