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Target
P2Y purinoceptor 14
Ligand
BDBM50304041
Substrate
n/a
Meas. Tech.
ChEMBL_601358 (CHEMBL1045995)
EC50
460±n/a nM
Citation
 Ko, H; Das, A; Carter, RL; Fricks, IP; Zhou, Y; Ivanov, AA; Melman, A; Joshi, BV; Kovác, P; Hajduch, J; Kirk, KL; Harden, TK; Jacobson, KA Molecular recognition in the P2Y(14) receptor: Probing the structurally permissive terminal sugar moiety of uridine-5'-diphosphoglucose. Bioorg Med Chem 17:5298-311 (2009) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 14
Synonyms:
P2Y14_HUMAN | P2RY14 | GPR105 | KIAA0001 | Purinergic receptor P2Y14 | Insulin Receptor-Related Protein (INSRR)
Type:
PROTEIN
Mol. Mass.:
38991.62
Organism:
Human
Description:
ChEMBL_1502487
Residue:
338
Sequence:
MINSTSTQPPDESCSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFIIYLKNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRYYKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKSELGRKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFSIVFVFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQPFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL
  
Inhibitor
Name:
BDBM50304041
Synonyms:
Diphosphoric Acid 1''-alpha-D-[5'']Arabinofuranosyl Ester 2-(uridin-5'-yl)ester | CHEMBL593842
Type:
Small organic molecule
Emp. Form.:
C14 H22 N2 O16 P2
Mol. Mass.:
536.2758
SMILES:
O[C@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)[C@@H](O)[C@@H]1O |r|
Structure:
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