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Target
P2Y purinoceptor 14
Ligand
BDBM50304044
Substrate
n/a
Meas. Tech.
ChEMBL_601358 (CHEMBL1045995)
EC50
951±n/a nM
Citation
 Ko, H; Das, A; Carter, RL; Fricks, IP; Zhou, Y; Ivanov, AA; Melman, A; Joshi, BV; Kovác, P; Hajduch, J; Kirk, KL; Harden, TK; Jacobson, KA Molecular recognition in the P2Y(14) receptor: Probing the structurally permissive terminal sugar moiety of uridine-5'-diphosphoglucose. Bioorg Med Chem 17:5298-311 (2009) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 14
Synonyms:
P2Y14_HUMAN | P2RY14 | GPR105 | KIAA0001 | Purinergic receptor P2Y14 | Insulin Receptor-Related Protein (INSRR)
Type:
PROTEIN
Mol. Mass.:
38991.62
Organism:
Human
Description:
ChEMBL_1502487
Residue:
338
Sequence:
MINSTSTQPPDESCSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFIIYLKNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRYYKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKSELGRKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFSIVFVFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQPFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL
  
Inhibitor
Name:
BDBM50304044
Synonyms:
[({[(2R,3R,4S,5S,6S)-6-[(2-{[(tert-butoxy)carbonyl]amino}ethyl)carbamoyl]-3,4,5-trihydroxyoxan-2-yl]oxy}(hydroxy)phosphoryl)oxy]({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy})phosphinic acid | CHEMBL594703
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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