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Target
Amine oxidase [flavin-containing] B
Ligand
BDBM15613
Substrate
n/a
Meas. Tech.
ChEMBL_601026 (CHEMBL1069163)
Ki
1080±n/a nM
Citation
 Gökhan-Kelekçi, N; Simsek, OO; Ercan, A; Yelekçi, K; Sahin, ZS; Isik, S; Uçar, G; Bilgin, AA Synthesis and molecular modeling of some novel hexahydroindazole derivatives as potent monoamine oxidase inhibitors. Bioorg Med Chem 17:6761-72 (2009) [PubMed]  Article 
Target
Name:
Amine oxidase [flavin-containing] B
Synonyms:
Monoamine oxidase B (rMAO-B) | Monoamine oxidase | Monoamine oxidase B (MAO-B) | Monoamine oxidase-B (MAO-B) | Amine oxidase [flavin-containing] B | Amine oxidase (flavin-containing) B | Monoamine oxidase type B (MAOB) | AOFB_RAT | Maob | Monoamine Oxidase Type B (MAO-B)
Type:
Enzyme
Mol. Mass.:
58469.65
Organism:
Rat
Description:
P19643
Residue:
520
Sequence:
MSNKCDVIVVGGGISGMAAAKLLHDCGLSVVVLEARDRVGGRTYTIRNKNVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHFVKGKSYAFRGPFPPVWNPITYLDYNNLWRTMDEMGQEIPSDAPWKAPLAEEWDYMTMKELLDKICWTNSTKQIATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFIGGSGQVSERIKDILGDRVKLERPVIHIDQTGENVVVKTLNHEIYEAKYVISAIPPVLGMKIHHSPPLPILRNQLITRVPLGSVIKCMVYYKEPFWRKKDFCGTMVIEGEEAPIAYTLDDTKPDGSCAAIMGFILAHKARKLVRLTKEERLRKLCELYAKVLNSQEALQPVHYEEKNWCEEQYSGGCYTAYFPPGILTQYGRVLRQPVGKIFFAGTETASHWSGYMEGAVEAGERAAREILHAIGKIPEDEIWQPEPESVDVPARPITNTFLERHLPSVPGLLKLLGLTTILSATALGFLAHKKGLFVRF
  
Inhibitor
Name:
BDBM15613
Synonyms:
MCL | Aurorix | 4-chloro-N-[2-(morpholin-4-yl)ethyl]benzamide | CHEMBL86304 | 4-chloro-N-(2-morpholin-4-ylethyl)benzamide | Moclobemide
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: