Reaction Details Report a problem with these data
Target
Ribonuclease pancreatic
Ligand
BDBM50304292
Substrate
n/a
Meas. Tech.
ChEMBL_606135 (CHEMBL1073967)
Ki
132000±n/a nM
Citation
 Debnath, J; Dasgupta, S; Pathak, T Inhibition of ribonuclease A by nucleoside-dibasic acid conjugates. Bioorg Med Chem 17:6491-5 (2009) [PubMed]  Article 
Target
Name:
Ribonuclease pancreatic
Synonyms:
RIB1 | RNAS1_HUMAN | RNASE1 | RNAse A | RNS1 | Ribonuclease A | Ribonuclease pancreatic
Type:
Protein
Mol. Mass.:
17653.66
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
156
Sequence:
MALEKSLVRLLLLVLILLVLGWVQPSLGKESRAKKFQRQHMDSDSSPSSSSTYCNQMMRRRNMTQGRCKPVNTFVHEPLVDVQNVCFQEKVTCKNGQGNCYKSNSSMHITDCRLTNGSRYPNCAYRTSPKERHIIVACEGSPYVPVHFDASVEDST
  
Inhibitor
Name:
BDBM50304292
Synonyms:
2-((2S,3S,5R)-2-(hydroxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-ylamino)-2-oxoacetic acid | CHEMBL593706
Type:
Small organic molecule
Emp. Form.:
C12H15N3O7
Mol. Mass.:
313.2634
SMILES:
Cc1cn([C@H]2C[C@H](NC(=O)C(O)=O)[C@@H](CO)O2)c(=O)[nH]c1=O |r|
Structure:
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