Reaction Details Report a problem with these data
Target
C5a anaphylatoxin chemotactic receptor 1
Ligand
BDBM50305735
Substrate
n/a
Meas. Tech.
ChEMBL_604754 (CHEMBL1072548)
IC50
>60000±n/a nM
Citation
 Chen, JJ; Cole, DC; Ciszewski, G; Crouse, K; Ellingboe, JW; Nowak, P; Tawa, GJ; Berstein, G; Li, W Identification of a new class of small molecule C5a receptor antagonists. Bioorg Med Chem Lett 20:662-4 (2010) [PubMed]  Article 
Target
Name:
C5a anaphylatoxin chemotactic receptor 1
Synonyms:
C5AR1_RAT | C5ar1 | C5r1 | C5a anaphylatoxin chemotactic receptor
Type:
PROTEIN
Mol. Mass.:
39427.21
Organism:
Rat
Description:
ChEMBL_604754
Residue:
352
Sequence:
MDPISNDSSEITYDYSDGTPNPDMPADGVYIPKMEPGDIAALIIYLAVFLVGVTGNALVVWVTAFEAKRTVNAIWFLNLAVADLLSCLALPILFTSIVKHNHWPFGDQACIVLPSLILLNMYSSILLLATISADRFLLVFKPIWCQKFRRPGLAWMACGVTWVLALLLTIPSFVFRRIHKDPYSDSILCNIDYSKGPFFIEKAIAILRLMVGFVLPLLTLNICYTFLLIRTWSRKATRSTKTLKVVMAVVTCFFVFWLPYQVTGVILAWLPRSSSTFQSVERLNSLCVSLAYINCCVNPIIYVMAGQGFHGRLRRSLPSIIRNVLSEDSLGRDSKSFTRSTMDTSTQKSQAV
  
Inhibitor
Name:
BDBM50305735
Synonyms:
N,N'-(1,2-phenylene)bis(N-methyl-1-phenylmethanesulfonamide) | CHEMBL595990
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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