Reaction Details Report a problem with these data
Target
C-X-C chemokine receptor type 4
Ligand
BDBM50305735
Substrate
n/a
Meas. Tech.
ChEMBL_604756 (CHEMBL1072550)
IC50
>60000±n/a nM
Citation
 Chen, JJ; Cole, DC; Ciszewski, G; Crouse, K; Ellingboe, JW; Nowak, P; Tawa, GJ; Berstein, G; Li, W Identification of a new class of small molecule C5a receptor antagonists. Bioorg Med Chem Lett 20:662-4 (2010) [PubMed]  Article 
Target
Name:
C-X-C chemokine receptor type 4
Synonyms:
C-X-C chemokine receptor type 4 | NPYRL | CXCR-4 | HM89 | CXC-R4 | SDF-1 receptor | CD_antigen=CD184 | Stromal cell-derived factor 1 receptor | LCR1 | LESTR | Fusin | Leukocyte-derived seven transmembrane domain receptor | FB22 | C-X-C chemokine receptor type 4 (CXCR4) | CXCR4_HUMAN | CXCR4
Type:
Enzyme
Mol. Mass.:
39754.61
Organism:
Human
Description:
P61073
Residue:
352
Sequence:
MEGISIYTSDNYTEEMGSGDYDSMKEPCFREENANFNKIFLPTIYSIIFLTGIVGNGLVILVMGYQKKLRSMTDKYRLHLSVADLLFVITLPFWAVDAVANWYFGNFLCKAVHVIYTVNLYSSVLILAFISLDRYLAIVHATNSQRPRKLLAEKVVYVGVWIPALLLTIPDFIFANVSEADDRYICDRFYPNDLWVVVFQFQHIMVGLILPGIVILSCYCIIISKLSHSKGHQKRKALKTTVILILAFFACWLPYYIGISIDSFILLEIIKQGCEFENTVHKWISITEALAFFHCCLNPILYAFLGAKFKTSAQHALTSVSRGSSLKILSKGKRGGHSSVSTESESSSFHSS
  
Inhibitor
Name:
BDBM50305735
Synonyms:
N,N'-(1,2-phenylene)bis(N-methyl-1-phenylmethanesulfonamide) | CHEMBL595990
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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