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Target
D(1B) dopamine receptor
Ligand
BDBM50306440
Substrate
n/a
Meas. Tech.
ChEMBL_609908 (CHEMBL1074770)
Ki
2.5±n/a nM
Citation
 Sasikumar, TK; Burnett, DA; Greenlee, WJ; Smith, M; Fawzi, A; Zhang, H; Lachowicz, JE Remote functionalization of SCH 39166: discovery of potent and selective benzazepine dopamine D1 receptor antagonists. Bioorg Med Chem Lett 20:832-5 (2010) [PubMed]  Article 
Target
Name:
D(1B) dopamine receptor
Synonyms:
DOPAMINE D5 | dopamine receptor D5 | D(5) dopamine receptor | D1beta dopamine receptor | DRD5_HUMAN | DRD5 | DRD1B | DRD1L2
Type:
Protein
Mol. Mass.:
52943.41
Organism:
Human
Description:
P21918
Residue:
477
Sequence:
MLPPGSNGTAYPGQFALYQQLAQGNAVGGSAGAPPLGPSQVVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGAFCDVWVAFDIMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLAWTLSILISFIPVQLNWHRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAACAPDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVSETTFDVFVWFGWANSSLNPVIYAFNADFQKVFAQLLGCSHFCSRTPVETVNISNELISYNQDIVFHKEIAAAYIHMMPNAVTPGNREVDNDEEEGPFDRMFQIYQTSPDGDPVAESVWELDCEGEISLDKITPFTPNGFH
  
Inhibitor
Name:
BDBM50306440
Synonyms:
11-chloro-12-hydroxy-7-methyl-6,6a,7,8,9,13b-hexahydro-5H-benzo[d]naphtho[2,1-b]azepine-4-carbaldehyde O-benzyl oxime | CHEMBL599135
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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