Reaction Details Report a problem with these data
Target
N-acylethanolamine-hydrolyzing acid amidase
Ligand
BDBM50309176
Substrate
n/a
Meas. Tech.
ChEMBL_608785 (CHEMBL1068377)
IC50
8300±n/a nM
Citation
 Saturnino, C; Petrosino, S; Ligresti, A; Palladino, C; De Martino, G; Bisogno, T; Di Marzo, V Synthesis and biological evaluation of new potential inhibitors of N-acylethanolamine hydrolyzing acid amidase. Bioorg Med Chem Lett 20:1210-3 (2010) [PubMed]  Article 
Target
Name:
N-acylethanolamine-hydrolyzing acid amidase
Synonyms:
N-acylsphingosine-amidohydrolase | Acid ceramidase-like protein | N-acylsphingosine amidohydrolase-like | ASAH-like protein | NAAA_HUMAN | NAAA | ASAHL | PLT | N-acylethanolamine-hydrolyzing acid amidase
Type:
Enzyme
Mol. Mass.:
40073.12
Organism:
Human
Description:
Q02083
Residue:
359
Sequence:
MRTADREARPGLPSLLLLLLAGAGLSAASPPAAPRFNVSLDSVPELRWLPVLRHYDLDLVRAAMAQVIGDRVPKWVHVLIGKVVLELERFLPQPFTGEIRGMCDFMNLSLADCLLVNLAYESSVFCTSIVAQDSRGHIYHGRNLDYPFGNVLRKLTVDVQFLKNGQIAFTGTTFIGYVGLWTGQSPHKFTVSGDERDKGWWWENAIAALFRRHIPVSWLIRATLSESENFEAAVGKLAKTPLIADVYYIVGGTSPREGVVITRNRDGPADIWPLDPLNGAWFRVETNYDHWKPAPKEDDRRTSAIKALNATGQANLSLEALFQILSVVPVYNNFTIYTTVMSAGSPDKYMTRIRNPSRK
  
Inhibitor
Name:
BDBM50309176
Synonyms:
N-Pentadecyl-benzamide | N-pentadecylbenzamide | CHEMBL190429
Type:
Small organic molecule
Emp. Form.:
C22 H37 N O
Mol. Mass.:
331.53528
SMILES:
CCCCCCCCCCCCCCCNC(=O)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: