Reaction Details Report a problem with these data
Target
Ribonuclease pancreatic
Ligand
BDBM50233301
Substrate
n/a
Meas. Tech.
ChEMBL_620094 (CHEMBL1109349)
pH
6±n/a
Ki
20100±n/a nM
Comments
extracted
Citation
 Dossi, K; Tsirkone, VG; Hayes, JM; Matousek, J; Poucková, P; Soucek, J; Zadinova, M; Zographos, SE; Leonidas, DD Mapping the ribonucleolytic active site of bovine seminal ribonuclease. The binding of pyrimidinyl phosphonucleotide inhibitors. Eur J Med Chem 44:4496-508 (2009) [PubMed]  Article 
Target
Name:
Ribonuclease pancreatic
Synonyms:
CAM-RNase A | RNAS1_BOVIN | RNASE1 | RNAse A | RNS1
Type:
Enzyme
Mol. Mass.:
16468.79
Organism:
Bison bison (American bison)
Description:
carboxamidomethylated RNase A
Residue:
150
Sequence:
MALKSLVLLSLLVLVLLLVRVQPSLGKETAAAKFERQHMDSSTSAASSSNYCNQMMKSRNLTKDRCKPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPNCAYKTTQANKHIIVACEGNPYVPVHFDASV
  
Inhibitor
Name:
BDBM50233301
Synonyms:
CHEMBL258728 | cytidine-3'-monophosphate
Type:
Small organic molecule
Emp. Form.:
C9H14N3O8P
Mol. Mass.:
323.1965
SMILES:
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](OP(O)(O)=O)[C@H]2O)c(=O)n1 |r|
Structure:
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