Reaction Details Report a problem with these data
Target
Prostaglandin D2 receptor
Ligand
BDBM50312906
Substrate
n/a
Meas. Tech.
ChEMBL_615903 (CHEMBL1102917)
IC50
5900±n/a nM
Citation
 Grimstrup, M; Receveur, JM; Rist, Ø; Frimurer, TM; Nielsen, PA; Mathiesen, JM; Högberg, T Exploration of SAR features by modifications of thiazoleacetic acids as CRTH2 antagonists. Bioorg Med Chem Lett 20:1638-41 (2010) [PubMed]  Article 
Target
Name:
Prostaglandin D2 receptor
Synonyms:
PD2R_MOUSE | Prostanoid DP receptor | Ptgdr
Type:
PROTEIN
Mol. Mass.:
40018.63
Organism:
Mus musculus
Description:
ChEMBL_788408
Residue:
357
Sequence:
MNESYRCQTSTWVERGSSATMGAVLFGAGLLGNLLALVLLARSGLGSCRPGPLHPPPSVFYVLVCGLTVTDLLGKCLISPMVLAAYAQNQSLKELLPASGNQLCETFAFLMSFFGLASTLQLLAMAVECWLSLGHPFFYQRHVTLRRGVLVAPVVAAFCLAFCALPFAGFGKFVQYCPGTWCFIQMIHKERSFSVIGFSVLYSSLMALLVLATVVCNLGAMYNLYDMHRRQRHYPHRCSRDRAQSGSDYRHGSLHPLEELDHFVLLALMTVLFTMCSLPLIYRAYYGAFKLENKAEGDSEDLQALRFLSVISIVDPWIFIIFRTSVFRMLFHKVFTRPLIYRNWSSHSQQSNVESTL
  
Inhibitor
Name:
BDBM50312906
Synonyms:
2-(2-(bis(4-fluorophenyl)methyl)-4-(3-fluorophenyl)pyrimidin-5-yl)acetic acid | CHEMBL1088284
Type:
Small organic molecule
Emp. Form.:
C25H17F3N2O2
Mol. Mass.:
434.4099
SMILES:
OC(=O)Cc1cnc(nc1-c1cccc(F)c1)C(c1ccc(F)cc1)c1ccc(F)cc1
Structure:
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