Reaction Details Report a problem with these data
Target
P2Y purinoceptor 2
Ligand
BDBM50319128
Substrate
n/a
Meas. Tech.
ChEMBL_635658 (CHEMBL1119550)
EC50
>10000±n/a nM
Citation
 Maruoka, H; Barrett, MO; Ko, H; Tosh, DK; Melman, A; Burianek, LE; Balasubramanian, R; Berk, B; Costanzi, S; Harden, TK; Jacobson, KA Pyrimidine ribonucleotides with enhanced selectivity as P2Y(6) receptor agonists: novel 4-alkyloxyimino, (S)-methanocarba, and 5'-triphosphate gamma-ester modifications. J Med Chem 53:4488-501 (2010) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 2
Synonyms:
P2Y purinoceptor 2 | Purinergic receptor | P2U purinoceptor 1 | ATP receptor | P2U1 | P2Y2 | P2RY2_HUMAN | P2RY2 | P2RU1 | Purinergic receptor P2Y2
Type:
PROTEIN
Mol. Mass.:
42299.21
Organism:
Human
Description:
ChEMBL_1455361
Residue:
377
Sequence:
MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGRVTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAKRKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSCLDPVLYFLAGQRLVRFARDAKPPTGPSPATPARRRLGLRRSDRTDMQRIEDVLGSSEDSRRTESTPAGSENTKDIRL
  
Inhibitor
Name:
BDBM50319128
Synonyms:
N4-Methoxycytidine 5-Phenyltriphosphate TriethylammoniumSalt | CHEMBL1083265
Type:
Small organic molecule
Emp. Form.:
C16 H22 N3 O15 P3 . C6 H15 N
Mol. Mass.:
690.46826
SMILES:
CONc1ccn([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)Oc3ccccc3)[C@@H](O)[C@H]2O)c(=O)n1 |r|
Structure:
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