Reaction Details Report a problem with these data
Target
P2Y purinoceptor 4
Ligand
BDBM50319129
Substrate
n/a
Meas. Tech.
ChEMBL_635652 (CHEMBL1119544)
EC50
6450±n/a nM
Citation
 Maruoka, H; Barrett, MO; Ko, H; Tosh, DK; Melman, A; Burianek, LE; Balasubramanian, R; Berk, B; Costanzi, S; Harden, TK; Jacobson, KA Pyrimidine ribonucleotides with enhanced selectivity as P2Y(6) receptor agonists: novel 4-alkyloxyimino, (S)-methanocarba, and 5'-triphosphate gamma-ester modifications. J Med Chem 53:4488-501 (2010) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 4
Synonyms:
P2P | P2Y purinoceptor 4 | P2Y4 | UNR | Uridine nucleotide receptor | P2RY4_HUMAN | P2RY4 | NRU | Pyrimidinergic receptor P2Y4
Type:
PROTEIN
Mol. Mass.:
40977.17
Organism:
Human
Description:
ChEMBL_751027
Residue:
365
Sequence:
MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL
  
Inhibitor
Name:
BDBM50319129
Synonyms:
CHEMBL1204010 | CHEMBL1084020 | N4-Methoxycytidine 5'-Diphosphate triethylammonium Salt
Type:
Small organic molecule
Emp. Form.:
C10 H17 N3 O12 P2 . C6 H15 N
Mol. Mass.:
534.3924
SMILES:
CONc1ccn([C@@H]2O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c(=O)n1 |r|
Structure:
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