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Target
Carbonic anhydrase 6
Ligand
BDBM79403
Substrate
n/a
Meas. Tech.
ChEMBL_646959 (CHEMBL1217100)
Ki
990±n/a nM
Citation
 Carta, F; Temperini, C; Innocenti, A; Scozzafava, A; Kaila, K; Supuran, CT Polyamines inhibit carbonic anhydrases by anchoring to the zinc-coordinated water molecule. J Med Chem 53:5511-22 (2010) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 6
Synonyms:
CA-VI | CA6 | CAH6_HUMAN | Carbonate dehydratase VI | Carbonic Anhydrase VI | Carbonic anhydrase | Carbonic anhydrase 6 | Carbonic anhydrase 6 (CA VI) | Carbonic anhydrase 6 (CA-VI) | Carbonic anhydrase VI (CA VI) | Salivary carbonic anhydrase | Secreted carbonic anhydrase
Type:
Enzyme
Mol. Mass.:
35371.40
Organism:
Homo sapiens (Human)
Description:
P23280
Residue:
308
Sequence:
MRALVLLLSLFLLGGQAQHVSDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNKTIHNDYRRTQPLNHRVVESNFPNQEYTLGSEFQFYLHKIEEILDYLRRALN
  
Inhibitor
Name:
BDBM79403
Synonyms:
3-aminopropyl-[4-(3-aminopropylamino)butyl]amine;hydrochloride | CHEMBL23194 | MLS002472980 | N,N''-bis(3-aminopropyl)butane-1,4-diamine;hydrochloride | N,N''-bis(3-azanylpropyl)butane-1,4-diamine;hydrochloride | N,N'-bis(3-aminopropyl)butane-1,4-diamine | SMR001397086 | Spermine | cid_5351186 | spermidine 3HCl
Type:
Small organic molecule
Emp. Form.:
C10H26N4
Mol. Mass.:
202.3402
SMILES:
NCCCNCCCCNCCCN
Structure:
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