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Target
Heat shock cognate 71 kDa protein
Ligand
BDBM31995
Substrate
n/a
Meas. Tech.
ChEMBL_675327 (CHEMBL1273364)
Kd
110±n/a nM
Citation
 Massey, AJ ATPases as drug targets: insights from heat shock proteins 70 and 90. J Med Chem 53:7280-6 (2010) [PubMed]  Article 
Target
Name:
Heat shock cognate 71 kDa protein
Synonyms:
HSC70 | HSP7C_BOVIN | HSPA8 | Heat shock 70 kDa protein 8
Type:
PROTEIN
Mol. Mass.:
71230.08
Organism:
Bos taurus
Description:
ChEMBL_675327
Residue:
650
Sequence:
MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELEKVCNPIITKLYQSAGGMPGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD
  
Inhibitor
Name:
BDBM31995
Synonyms:
ADP | Adenosine Diphosphate (ADP) | CHEMBL14830
Type:
Nucleoside or nucleotide
Emp. Form.:
C10H15N5O10P2
Mol. Mass.:
427.2011
SMILES:
Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O
Structure:
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