Target
D(4) dopamine receptor
Ligand
BDBM50122044
Substrate
n/a
Meas. Tech.
ChEMBL_675650 (CHEMBL1274011)
Ki
11.29±n/a nM
Citation
 Lacivita, EDe Giorgio, PLee, ITRodeheaver, SIWeiss, BAFracasso, CCaccia, SBerardi, FPerrone, RZhang, MRMaeda, JHiguchi, MSuhara, TSchetz, JALeopoldo, M Design, synthesis, radiolabeling, and in vivo evaluation of carbon-11 labeled N-[2-[4-(3-cyanopyridin-2-yl)piperazin-1-yl]ethyl]-3-methoxybenzamide, a potential positron emission tomography tracer for the dopamine D(4) receptors. J Med Chem 53:7344-55 (2010) [PubMed]  Article 
Target
Name:
D(4) dopamine receptor
Synonyms:
D(4) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.4 | DRD4_RAT | Dopamine receptor | Drd4
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41307.65
Organism:
RAT
Description:
DOPAMINE D4.4 0 RAT::P30729
Residue:
387
Sequence:
MGNSSATGDGGLLAGRGPESLGTGTGLGGAGAAALVGGVLLIGMVLAGNSLVCVSVASERILQTPTNYFIVSLAAADLLLAVLVLPLFVYSEVQGGVWLLSPRLCDTLMAMDVMLCTASIFNLCAISVDRFVAVTVPLRYNQQGQCQLLLIAATWLLSAAVAAPVVCGLNDVPGRDPTVCCLEDRDYVVYSSICSFFLPCPLMLLLYWATFRGLRRWEAARHTKLHSRAPRRPSGPGPPVSDPTQGPLFSDCPPPSPSLRTSPTVSSRPESDLSQSPCSPGCLLPDAALAQPPAPSSRRKRGAKITGRERKAMRVLPVVVGAFLMCWTPFFVVHITRALCPACFVSPRLVSAVTWLGYVNSALNPIIYTIFNAEFRSVFRKTLRLRC
  
Inhibitor
Name:
BDBM50122044
Synonyms:
CHEMBL345111 | N-{2-[4-(5-Chloro-pyridin-2-yl)-piperazin-1-yl]-ethyl}-3-methoxy-benzamide
Type:
Small organic molecule
Emp. Form.:
C19H23ClN4O2
Mol. Mass.:
374.865
SMILES:
COc1cccc(c1)C(=O)NCCN1CCN(CC1)c1ccc(Cl)cn1
Structure:
Search PDB for entries with ligand similarity: