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Target
Carbonic anhydrase 7
Ligand
BDBM50329828
Substrate
n/a
Meas. Tech.
ChEMBL_675714 (CHEMBL1272348)
Kd
10000±n/a nM
Citation
 Capkauskaite, E; Baranauskiene, L; Golovenko, D; Manakova, E; Gražulis, S; Tumkevičius, S; Matulis, D Indapamide-like benzenesulfonamides as inhibitors of carbonic anhydrases I, II, VII, and XIII. Bioorg Med Chem 18:7357-64 (2010) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 7
Synonyms:
CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII)
Type:
Enzyme
Mol. Mass.:
29664.11
Organism:
Homo sapiens (Human)
Description:
Human cloned isozyme.
Residue:
264
Sequence:
MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNNFRPPQPLKGRVVKASFRA
  
Inhibitor
Name:
BDBM50329828
Synonyms:
2-Chloro-5-{[2-(4-morpholinylmethyl)-1H-benzimidazol-1-yl]acetyl}benzenesulfona-mide | CHEMBL1271529
Type:
Small organic molecule
Emp. Form.:
C20H21ClN4O4S
Mol. Mass.:
448.923
SMILES:
NS(=O)(=O)c1cc(ccc1Cl)C(=O)Cn1c(CN2CCOCC2)nc2ccccc12
Structure:
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