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Target
Carbonic anhydrase 13
Ligand
BDBM50329831
Substrate
n/a
Meas. Tech.
ChEMBL_675715 (CHEMBL1272349)
Kd
400±n/a nM
Citation
 Capkauskaite, E; Baranauskiene, L; Golovenko, D; Manakova, E; Gražulis, S; Tumkevičius, S; Matulis, D Indapamide-like benzenesulfonamides as inhibitors of carbonic anhydrases I, II, VII, and XIII. Bioorg Med Chem 18:7357-64 (2010) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 13
Synonyms:
CA13 | CAH13_HUMAN | Carbonic anhydrase | Carbonic anhydrase 13 (CA XIII) | Carbonic anhydrase XIII (CA XIII)
Type:
Enzyme
Mol. Mass.:
29445.78
Organism:
Homo sapiens (Human)
Description:
Q8N1Q1
Residue:
262
Sequence:
MSRLSWGYREHNGPIHWKEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPSSAKIISNSGHSFNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAELHVVHWNSDKYPSFVEAAHEPDGLAVLGVFLQIGEPNSQLQKITDTLDSIKEKGKQTRFTNFDLLSLLPPSWDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAAFLVSNHRPPQPLKGRKVRASFH
  
Inhibitor
Name:
BDBM50329831
Synonyms:
2-Chloro-5-[(2-methyl-1H-benzimidazol-1-yl)acetyl]benzenesulfonamide | CHEMBL1272188 | N-alkylated benzimidazole derivative, 4b
Type:
Small organic molecule
Emp. Form.:
C16H14ClN3O3S
Mol. Mass.:
363.819
SMILES:
Cc1nc2ccccc2n1CC(=O)c1ccc(Cl)c(c1)S(N)(=O)=O
Structure:
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