Reaction Details Report a problem with these data
Target
SugE
Ligand
BDBM50053184
Substrate
n/a
Meas. Tech.
ChEMBL_693672 (CHEMBL1637940)
IC50
300±n/a nM
Citation
 Zioga, A; Whichard, JM; Kotsakis, SD; Tzouvelekis, LS; Tzelepi, E; Miriagou, V CMY-31 and CMY-36 cephalosporinases encoded by ColE1-like plasmids. Antimicrob Agents Chemother 53:1256-9 (2009) [PubMed]  Article 
Target
Name:
SugE
Synonyms:
SugE | Efflux transporter
Type:
PROTEIN
Mol. Mass.:
10901.14
Organism:
Salmonella newport
Description:
ChEMBL_693672
Residue:
105
Sequence:
MSWIVLLIAGLLEVVWAIGLKYTHGFTRLTPSIITIAAMIVSIAMLSWAMRTLPVGTAYAVWTGIGAVGAAITGILLLGESASPARLLSLGLIVAGIIGLKLSTH
  
Inhibitor
Name:
BDBM50053184
Synonyms:
(2S,3S,5R)-3-(2-Cyano-vinyl)-3-methyl-4,4,7-trioxo-4lambda 6-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid | (2S,3S,5R)-3-((Z)-2-Cyano-vinyl)-3-methyl-4,4,7-trioxo-4lambda*6*-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid | CHEMBL333078
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
C[C@]1(\C=C/C#N)[C@@H](N2[C@@H](CC2=O)S1(=O)=O)C(O)=O |r|
Structure:
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