Reaction Details Report a problem with these data
Target
D(3) dopamine receptor
Ligand
BDBM50336701
Substrate
n/a
Meas. Tech.
ChEMBL_723392 (CHEMBL1676194)
Kd
93±n/a nM
Citation
 Vendrell, M; Molero, A; González, S; Pérez-Capote, K; Lluis, C; McCormick, PJ; Franco, R; Cortés, A; Casadó, V; Albericio, F; Royo, M Biotin ergopeptide probes for dopamine receptors. J Med Chem 54:1080-90 (2011) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50336701
Synonyms:
(6aR,9R)-N-((2S)-1-((2S)-1-(3-(6-((S)-6-amino-6-oxo-5-(5-((3aR,4R,6aS)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexylamino)-6-oxohexylcarbamoyl)piperidin-1-yl)-3-(4-fluorophenyl)-1-oxopropan-2-ylamino)-3-(4-nitrophenyl)-1-oxopropan-2-yl)-7-methyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide | CHEMBL1673003
Type:
Small organic molecule
Emp. Form.:
C62H79FN12O10S
Mol. Mass.:
1203.428
SMILES:
CN1C[C@@H](C=C2[C@H]1Cc1c[nH]c3cccc2c13)C(=O)N[C@@H](Cc1ccc(cc1)[N+]([O-])=O)C(=O)N[C@@H](Cc1ccc(F)cc1)C(=O)N1CCCC(C1)C(=O)NCCCCCC(=O)NCCCC[C@H](NC(=O)CCCC[C@H]1SC[C@H]2NC(=O)N[C@@H]12)C(N)=O |r,c:4|
Structure:
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