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Target
Carbonic anhydrase 2
Ligand
BDBM26990
Substrate
n/a
Meas. Tech.
ChEMBL_735671 (CHEMBL1693486)
pH
7.5±n/a
Ki
40000±n/a nM
Comments
extracted
Citation
 Cincinelli, A; Martellini, T; Innocenti, A; Scozzafava, A; Supuran, CT Purification and inhibition studies with anions and sulfonamides of ana-carbonic anhydrase from the Antarctic seal Leptonychotes weddellii. Bioorg Med Chem 19:1847-51 (2011) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 2
Synonyms:
CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II)
Type:
Enzyme
Mol. Mass.:
29250.71
Organism:
Homo sapiens (Human)
Description:
P00918
Residue:
260
Sequence:
MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
  
Inhibitor
Name:
BDBM26990
Synonyms:
CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfide)(-1) | hydrosulfide | sulfanide
Type:
Ion
Emp. Form.:
HS
Mol. Mass.:
33.073
SMILES:
[SH-]
Structure:
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