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Target
Sialidase-4
Ligand
BDBM4706
Substrate
n/a
Meas. Tech.
ChEMBL_745979 (CHEMBL1775278)
IC50
22000±n/a nM
Citation
 Albohy, A; Mohan, S; Zheng, RB; Pinto, BM; Cairo, CW Inhibitor selectivity of a new class of oseltamivir analogs against viral neuraminidase over human neuraminidase enzymes. Bioorg Med Chem 19:2817-22 (2011) [PubMed]  Article 
Target
Name:
Sialidase-4
Synonyms:
NEU4 | NEUR4_HUMAN | Sialidase 4
Type:
PROTEIN
Mol. Mass.:
51579.82
Organism:
Homo sapiens (Human)
Description:
ChEMBL_960637
Residue:
484
Sequence:
MGVPRTPSRTVLFERERTGLTYRVPSLLPVPPGPTLLAFVEQRLSPDDSHAHRLVLRRGTLAGGSVRWGALHVLGTAALAEHRSMNPCPVHDAGTGTVFLFFIAVLGHTPEAVQIATGRNAARLCCVASRDAGLSWGSARDLTEEAIGGAVQDWATFAVGPGHGVQLPSGRLLVPAYTYRVDRRECFGKICRTSPHSFAFYSDDHGRTWRCGGLVPNLRSGECQLAAVDGGQAGSFLYCNARSPLGSRVQALSTDEGTSFLPAERVASLPETAWGCQGSIVGFPAPAPNRPRDDSWSVGPGSPLQPPLLGPGVHEPPEEAAVDPRGGQVPGGPFSRLQPRGDGPRQPGPRPGVSGDVGSWTLALPMPFAAPPQSPTWLLYSHPVGRRARLHMGIRLSQSPLDPRSWTEPWVIYEGPSGYSDLASIGPAPEGGLVFACLYESGARTSYDEISFCTFSLREVLENVPASPKPPNLGDKPRGCCWPS
  
Inhibitor
Name:
BDBM4706
Synonyms:
(2R,3R,4S)-3-acetamido-4-hydroxy-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid | 2,3-didehydro-2-deoxy-N-acetylneuraminic acid | CHEMBL96712 | DANA | Neu5Ac2en
Type:
Small organic molecule
Emp. Form.:
C11H17NO8
Mol. Mass.:
291.2546
SMILES:
CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@H](O)[C@H](O)CO)C(O)=O |r,c:7|
Structure:
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