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Target
Carbonic anhydrase 7
Ligand
BDBM50345217
Substrate
n/a
Meas. Tech.
ChEMBL_751966 (CHEMBL1785908)
Ki
71±n/a nM
Citation
 Hen, N; Bialer, M; Yagen, B; Maresca, A; Aggarwal, M; Robbins, AH; McKenna, R; Scozzafava, A; Supuran, CT Anticonvulsant 4-aminobenzenesulfonamide derivatives with branched-alkylamide moieties: X-ray crystallography and inhibition studies of human carbonic anhydrase isoforms I, II, VII, and XIV. J Med Chem 54:3977-81 (2011) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 7
Synonyms:
CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII)
Type:
Enzyme
Mol. Mass.:
29664.11
Organism:
Homo sapiens (Human)
Description:
Human cloned isozyme.
Residue:
264
Sequence:
MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNNFRPPQPLKGRVVKASFRA
  
Inhibitor
Name:
BDBM50345217
Synonyms:
2-Ethyl-N-(4-sulfamoyl-benzyl)-butyramide | 2-Ethyl-N-(4-sulfamoylbenzyl)butyramide | 2-ethyl-N-(4-sulfamoylbenzyl)butanamide | CHEMBL73460
Type:
Small organic molecule
Emp. Form.:
C13H20N2O3S
Mol. Mass.:
284.374
SMILES:
CCC(CC)C(=O)NCc1ccc(cc1)S(N)(=O)=O
Structure:
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