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Target
P2Y purinoceptor 2
Ligand
BDBM50345484
Substrate
n/a
Meas. Tech.
ChEMBL_751013 (CHEMBL1786668)
EC50
620±n/a nM
Citation
 Maruoka, H; Jayasekara, MP; Barrett, MO; Franklin, DA; de Castro, S; Kim, N; Costanzi, S; Harden, TK; Jacobson, KA Pyrimidine nucleotides with 4-alkyloxyimino and terminal tetraphosphated-ester modifications as selective agonists of the P2Y(4) receptor. J Med Chem 54:4018-33 (2011) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 2
Synonyms:
P2Y purinoceptor 2 | Purinergic receptor | P2U purinoceptor 1 | ATP receptor | P2U1 | P2Y2 | P2RY2_HUMAN | P2RY2 | P2RU1 | Purinergic receptor P2Y2
Type:
PROTEIN
Mol. Mass.:
42299.21
Organism:
Human
Description:
ChEMBL_1455361
Residue:
377
Sequence:
MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGRVTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAKRKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSCLDPVLYFLAGQRLVRFARDAKPPTGPSPATPARRRLGLRRSDRTDMQRIEDVLGSSEDSRRTESTPAGSENTKDIRL
  
Inhibitor
Name:
BDBM50345484
Synonyms:
N4-Benzyloxycytidine-5'-triphosphate | CHEMBL1784892
Type:
Small organic molecule
Emp. Form.:
C16H22N3O15P3
Mol. Mass.:
n/a
SMILES:
O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(NOCc2ccccc2)nc1=O |r|
Structure:
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