Reaction Details Report a problem with these data
Target
P2Y purinoceptor 6
Ligand
BDBM50319143
Substrate
n/a
Meas. Tech.
ChEMBL_751015 (CHEMBL1786670)
EC50
130±n/a nM
Citation
 Maruoka, H; Jayasekara, MP; Barrett, MO; Franklin, DA; de Castro, S; Kim, N; Costanzi, S; Harden, TK; Jacobson, KA Pyrimidine nucleotides with 4-alkyloxyimino and terminal tetraphosphated-ester modifications as selective agonists of the P2Y(4) receptor. J Med Chem 54:4018-33 (2011) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 6
Synonyms:
P2Y purinoceptor 6 | P2Y6 | P2RY6_HUMAN | P2RY6 | Pyrimidinergic receptor P2Y6
Type:
PROTEIN
Mol. Mass.:
36452.29
Organism:
Human
Description:
ChEMBL_1511151
Residue:
328
Sequence:
MEWDNGTGQALGLPPTTCVYRENFKQLLLPPVYSAVLAAGLPLNICVITQICTSRRALTRTAVYTLNLALADLLYACSLPLLIYNYAQGDHWPFGDFACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHKRGGRRAAWLVCVAVWLAVTTQCLPTAIFAATGIQRNRTVCYDLSPPALATHYMPYGMALTVIGFLLPFAALLACYCLLACRLCRQDGPAEPVAQERRGKAARMAVVVAAAFAISFLPFHITKTAYLAVRSTPGVPCTVLEAFAAAYKGTRPFASANSVLDPILFYFTQKKFRRRPHELLQKLTAKWQRQGR
  
Inhibitor
Name:
BDBM50319143
Synonyms:
CHEMBL1083764 | CHEMBL1198849 | N4-Methoxycytidine 5'-Triphosphate triethylammonium Salt
Type:
Small organic molecule
Emp. Form.:
C10 H18 N3 O15 P3 . C6 H15 N
Mol. Mass.:
614.3723
SMILES:
CONc1ccn([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c(=O)n1 |r|
Structure:
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