Reaction Details Report a problem with these data
Target
Mu-type opioid receptor
Ligand
BDBM50347164
Substrate
n/a
Meas. Tech.
ChEMBL_753521 (CHEMBL1798229)
Ki
22.3±n/a nM
Citation
 Nagase, H; Watanabe, A; Nemoto, T; Nakajima, M; Hasebe, K; Mochizuki, H; Fujii, H Synthesis of novel triplet drugs with 1,3,5-trioxazatriquinane skeletons and their pharmacologies. 1: Synthesis of triplet drugs with morphinan skeletons. Bioorg Med Chem Lett 21:4023-6 (2011) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50347164
Synonyms:
CHEMBL1797518
Type:
Small organic molecule
Emp. Form.:
C63H72N4O9
Mol. Mass.:
1029.2672
SMILES:
Oc1ccc2C[C@@H]3[C@@H]4CC[C@]5(O[C@@H]6N7[C@H]5O[C@]5(CC[C@H]8[C@H]9Cc%10ccc(O)c%11O[C@@H]5[C@]8(CCN9CC5CC5)c%10%11)[C@@H]7O[C@]65CC[C@H]6[C@H]7Cc8ccc(O)c9O[C@@H]5[C@]6(CCN7CC5CC5)c89)[C@@H]5Oc1c2[C@]45CCN3CC1CC1 |r|
Structure:
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