Reaction Details Report a problem with these data
Target
D(2) dopamine receptor
Ligand
BDBM50347558
Substrate
n/a
Meas. Tech.
ChEMBL_756833 (CHEMBL1803157)
EC50
16±n/a nM
Citation
 Reinart, R; Gyulai, Z; Berényi, S; Antus, S; Vonk, A; Rinken, A; Sipos, A New 2-thioether-substituted apomorphines as potent and selective dopamine D2 receptor agonists. Eur J Med Chem 46:2992-9 (2011) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50347558
Synonyms:
CHEMBL1802233
Type:
Small organic molecule
Emp. Form.:
C19H22N2O2S
Mol. Mass.:
342.455
SMILES:
CN1CCc2cc(SCCN)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 |r|
Structure:
Search PDB for entries with ligand similarity: