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Target
Arginase
Ligand
BDBM50350310
Substrate
n/a
Meas. Tech.
ChEMBL_762138 (CHEMBL1816209)
Ki
2000000±n/a nM
Citation
 Ilies, M; Di Costanzo, L; Dowling, DP; Thorn, KJ; Christianson, DW Binding ofa,a-disubstituted amino acids to arginase suggests new avenues for inhibitor design. J Med Chem 54:5432-43 (2011) [PubMed]  Article 
Target
Name:
Arginase
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
46502.96
Organism:
Plasmodium falciparum
Description:
ChEMBL_762136
Residue:
411
Sequence:
MLDTIESYIKSHKEKENLYVKKNVSIIGSPLAAGQPLGGVQLACDDLRKLGLHNVIDVLGWKYEDIGNIDNGDNEMKQEKKTNNYINNNDNNNDNNNDNNNDNNNNCYIPNGVIKEKKHDLSNNKMNGYVNHNFYGNYEENNVISTNDKYKNNCYYDNIRNIKEIGIFSKNLFDTMSNELRKKNFVLNIGGDHGVAFSSILSSLQMYQNLRVIWIDAHGDINIPETSPSGNYHGMTLAHTLGLFKKKVPYFEWSEKLTYLKPENTAIIGIRDIDAYEKIILKKCNINYYTIFDIEKNGIYNTICTALEKIDPNSNCPIHISLDIDSVDNVFAPGTGTVAKGGLNYREINLLMKILAETKRVVSMDLVEYNPSLDEVDKKVHGDSLPILDNATKTGKLCLELIARVLGYDIV
  
Inhibitor
Name:
BDBM50350310
Synonyms:
CHEMBL1812663
Type:
Small organic molecule
Emp. Form.:
C7H14BF2NO4
Mol. Mass.:
224.998
SMILES:
[NH3+]C(CCCCB(O)O)(C(F)F)C([O-])=O
Structure:
Search PDB for entries with ligand similarity: