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Target
Prostaglandin E2 receptor EP1 subtype
Ligand
BDBM50350366
Substrate
n/a
Meas. Tech.
ChEMBL_761104 (CHEMBL1815358)
Ki
>10000±n/a nM
Citation
 Iwahashi, M; Shimabukuro, A; Onoda, T; Matsunaga, Y; Okada, Y; Matsumoto, R; Nambu, F; Nakai, H; Toda, M Discovery of selective indole-based prostaglandin D2 receptor antagonist. Bioorg Med Chem 19:4574-88 (2011) [PubMed]  Article 
Target
Name:
Prostaglandin E2 receptor EP1 subtype
Synonyms:
Prostaglandin E1 | Prostaglandin E2 receptor EP1 subtype | PGE receptor, EP1 subtype | PE2R1_MOUSE | Ptger1 | Ptgerep1 | Prostanoid EP1 receptor
Type:
G-protein coupled receptor
Mol. Mass.:
43000.62
Organism:
Mouse
Description:
n/a
Residue:
405
Sequence:
MSPCGLNLSLADEAATCATPRLPNTSVVLPTGDNGTSPALPIFSMTLGAVSNVLALALLAQVAGRMRRRRSAATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALAVLAAMALAVALLPLVHVGRYELQYPGTWCFISLGPRGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRKTAGPDDRRRWGSRGPRLASASSASSITSATATLRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELGLTKSAWEASSLRSSRHSGFSHL
  
Inhibitor
Name:
BDBM50350366
Synonyms:
CHEMBL1813287
Type:
Small organic molecule
Emp. Form.:
C30H30N2O4
Mol. Mass.:
n/a
SMILES:
CCN1[C@@H](COc2ccc(C(=O)n3c(C)c(CC(O)=O)c4ccccc34)c(C)c2)Cc2ccccc12 |r|
Structure:
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