Target
Melatonin receptor type 1A
Ligand
BDBM50340329
Substrate
n/a
Meas. Tech.
ChEMBL_766803 (CHEMBL1827743)
Ki
0.24±n/a nM
Citation
 El Kazzouli, SGriffon du Bellay, ABerteina-Raboin, SDelagrange, PCaignard, DHGuillaumet, G Design and synthesis of 2-phenylimidazo[1,2-a]pyridines as a novel class of melatonin receptor ligands. Eur J Med Chem 46:4252-7 (2011) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1A
Synonyms:
MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A
Type:
Enzyme
Mol. Mass.:
39392.94
Organism:
Homo sapiens (Human)
Description:
P48039
Residue:
350
Sequence:
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
  
Inhibitor
Name:
BDBM50340329
Synonyms:
4-azamelatonin | CHEMBL1760944
Type:
Small organic molecule
Emp. Form.:
C12H15N3O2
Mol. Mass.:
233.2664
SMILES:
COc1ccc2[nH]cc(CCNC(C)=O)c2n1
Structure:
Search PDB for entries with ligand similarity: