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Target
Acetylcholine-binding protein
Ligand
BDBM50353944
Substrate
n/a
Meas. Tech.
ChEMBL_770043 (CHEMBL1832418)
Ki
2511.89±n/a nM
Citation
 Akdemir, A; Rucktooa, P; Jongejan, A; Elk, R; Bertrand, S; Sixma, TK; Bertrand, D; Smit, AB; Leurs, R; de Graaf, C; de Esch, IJ Acetylcholine binding protein (AChBP) as template for hierarchical in silico screening procedures to identify structurally novel ligands for the nicotinic receptors. Bioorg Med Chem 19:6107-19 (2011) [PubMed]  Article 
Target
Name:
Acetylcholine-binding protein
Synonyms:
Acetylcholine Binding protein | Acetylcholine-binding protein (Ls-AchBP) | AchBP | ACHP_LYMST | Acetylcholine-binding protein (AchBP) | ACh-binding protein
Type:
n/a
Mol. Mass.:
26055.52
Organism:
Great pond snail
Description:
Soluble acetylcholine receptor
Residue:
229
Sequence:
MRRNIFCLACLWIVQACLSLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRSEIL
  
Inhibitor
Name:
BDBM50353944
Synonyms:
CHEMBL1831036
Type:
Small organic molecule
Emp. Form.:
C20H23N3
Mol. Mass.:
n/a
SMILES:
c1ccc(C2CCN(CCc3nc4ccccc4[nH]3)CC2)cc1
Structure:
Search PDB for entries with ligand similarity: