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Target
Proton-coupled amino acid transporter 1
Ligand
BDBM50017225
Substrate
n/a
Meas. Tech.
ChEMBL_788189 (CHEMBL1919336)
Ki
1900000±n/a nM
Citation
 Thondorf, I; Voigt, V; Schäfer, S; Gebauer, S; Zebisch, K; Laug, L; Brandsch, M Three-dimensional quantitative structure-activity relationship analyses of substrates of the human proton-coupled amino acid transporter 1 (hPAT1). Bioorg Med Chem 19:6409-18 (2011) [PubMed]  Article 
Target
Name:
Proton-coupled amino acid transporter 1
Synonyms:
Solute carrier family 36 member 1 | hPAT1 | Proton/amino acid transporter 1 | S36A1_HUMAN | SLC36A1 | PAT1
Type:
PROTEIN
Mol. Mass.:
53078.06
Organism:
Human
Description:
ChEMBL_788189
Residue:
476
Sequence:
MSTQRLRNEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGNIGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTVMYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNETVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLVSLVMIYQFIVQRIPDPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVTILYISLGCLGYLQFGANIQGSITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIPFFVSRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLEVTTFYSEGMSPLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINSTCAFI
  
Inhibitor
Name:
BDBM50017225
Synonyms:
methylaminoacetic acid | Sar | N-methylaminoacetic acid | (methylamino)ethanoic acid | CHEMBL304383 | sarcosinic acid | (methylamino)acetic acid | sarcosine
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
CNCC(=O)O
Structure:
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