Reaction Details Report a problem with these data
Target
Proton-coupled amino acid transporter 1
Ligand
BDBM50357228
Substrate
n/a
Meas. Tech.
ChEMBL_788189 (CHEMBL1919336)
Ki
2500000±n/a nM
Citation
Thondorf, I; Voigt, V; Schäfer, S; Gebauer, S; Zebisch, K; Laug, L; Brandsch, M Three-dimensional quantitative structure-activity relationship analyses of substrates of the human proton-coupled amino acid transporter 1 (hPAT1). Bioorg Med Chem 19:6409-18 (2011) [PubMed] Article
More Info.:
Target
Name:
Proton-coupled amino acid transporter 1
Synonyms:
PAT1 | Proton/amino acid transporter 1 | S36A1_HUMAN | SLC36A1 | Solute carrier family 36 member 1 | hPAT1
Type:
PROTEIN
Mol. Mass.:
53078.06
Organism:
Human
Description:
ChEMBL_788189
Residue:
476
Sequence:
MSTQRLRNEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGNIGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTVMYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNETVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLVSLVMIYQFIVQRIPDPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVTILYISLGCLGYLQFGANIQGSITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIPFFVSRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLEVTTFYSEGMSPLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINSTCAFI