Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM50359500
Substrate
n/a
Meas. Tech.
ChEMBL_792735 (CHEMBL1930650)
EC50
2500±n/a nM
Citation
 Lewin, AH; Miller, GM; Gilmour, B Trace amine-associated receptor 1 is a stereoselective binding site for compounds in the amphetamine class. Bioorg Med Chem 19:7044-8 (2011) [PubMed]  Article 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
Trace amine receptor 1 | TaR-1 | TAAR1_MACMU | TAAR1 | TA1 | TAR1 | TRAR1
Type:
PROTEIN
Mol. Mass.:
38812.87
Organism:
Rhesus macaque
Description:
ChEMBL_792735
Residue:
338
Sequence:
MPFCHNIINISCVKNNWSNDVRASLYSLMALIILTTLVGNLIVIVSISHFKQLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVCDPLRYKAKINILVVCVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGGCSVFFSKISGVLAFMTSFYIPGSIMLCIYYRIYLIAKEQARSINDANQKLQIGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFVCTVIDPFLHYTIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRKALKMILFGKIFQKDSSRCKLFLESSS
  
Inhibitor
Name:
BDBM50359500
Synonyms:
CHEMBL1927030 | (R)Methamphetamine
Type:
Small organic molecule
Emp. Form.:
C10H15N
Mol. Mass.:
n/a
SMILES:
CN[C@H](C)Cc1ccccc1 |r|
Structure:
Search PDB for entries with ligand similarity: