Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM50359499
Substrate
n/a
Meas. Tech.
ChEMBL_792737 (CHEMBL1930652)
EC50
890±n/a nM
Citation
 Lewin, AH; Miller, GM; Gilmour, B Trace amine-associated receptor 1 is a stereoselective binding site for compounds in the amphetamine class. Bioorg Med Chem 19:7044-8 (2011) [PubMed]  Article 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
Trace amine receptor 1 (TARR1) | Trace amine-associated receptor1 | TAAR1_RAT | Taar1 | Ta1 | Tar1 | Trar1 | Trace amine-associated receptor 1 (TAAR1) | Trace amine-associated receptor 1
Type:
Enzyme
Mol. Mass.:
38034.73
Organism:
Rat
Description:
Q923Y9
Residue:
332
Sequence:
MHLCHNSANISHTNSNWSRDVRASLYSLISLIILTTLVGNLIVIISISHFKQLHTPTNWLLHSMAVVDFLLGCLVMPYSMVRTVEHCWYFGELFCKLHTSTDIMLSSASILHLAFISIDRYYAVCDPLRYKAKINLAAIFVMILISWSLPAVFAFGMIFLELNLEGVEELYHNQVFCLRGCFPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRANLQVGLEGESRAPQSKETKAAKTLGIMVGVFLLCWCPFFFCMVLDPFLGYVIPPTLNDTLNWFGYLNSAFNPMVYAFFYPWFRRALKMVLFGKIFQKDSSRSKLFL
  
Inhibitor
Name:
BDBM50359499
Synonyms:
METHAMPHETAMINE | (S)Methamphetamine
Type:
Small organic molecule
Emp. Form.:
C10H15N
Mol. Mass.:
n/a
SMILES:
C[C@@H](Cc1ccccc1)NC
Structure:
Search PDB for entries with ligand similarity: